CREATING A PARADIGM SHIFT IN COMPLEX INTERVENTIONS IN PERIPHERAL AND CORONARY ARTERIAL DISEASES (PAD AND CAD)

We deliver a single-step, wire-free intraplaque crossing solution that modifies plaque and prepares the vessel for further treatment – all in one smooth move. It’s not an iteration. It’s a rewrite.

Female doctor smiling and holding a tablet while talking with a patient in a medical office.

The AngioSafe Mission

AngioSafe was founded to flip the script in revascularization. Our technology doesn’t just improve the process – it replaces four families of devices, replicating outcomes and reducing complications.

We’re building a pipeline of game-changing devices that make complex interventions safer, faster and more predictable, while empowering physicians to more confidently address severely stenosed vessels, including chronic total occlusions (CTOs).

AngioSafe is the first philanthropic-funded medical device company in the world. Our investors are dedicated to fostering a better future for patients and communities and have committed to donating a percentage of their returns to various not-for-profit organizations around the world.

One Concept. All Cath Labs. All Interventionalists. Patented.

A female doctor in scrubs and a white coat, holding a clipboard, smiles and talks to an older female patient.

Flow Is Life. We Restore It.

Blood flow isn’t optional. It’s the first requirement for healing, limb salvage, and quality of life. But over 200 million patients are living with blocked vessels because traditional tools are just too slow, too risky, or too complex.

AngioSafe empowers more physicians to treat more patients—sooner, safer, and smarter.

Disruption Backed by  Deep Experience.

We’re not new to this. Our founding team has shaped the industry—bringing first-in-class therapies to hundreds of millions of patients across respiratory, neurology, cardiovascular, vascular imaging, diagnostics, and orthopedic medicine, ranging from small start-ups to global multinational companies.

We’re bringing that same firepower to endovascular care. And we’re not stopping until no CTO goes untreated.

A doctor holding a tablet smiles while talking to an older male patient in a plaid shirt during a medical consultation.

AngioSafe Leadership

AngioSafe is backed by a combined 200+ years of life science experience.

Sarvajna Dwivedi, Ph.D.

President and CEO, Co-founder, Investor, Board Member
Built Pearl Therapeutics to a $1.15B acquisition by AstraZeneca
Deep experience in drug and device combination field

Mallik Thatipelli, MD

Founder, Inventor, Chief of Innovation, and Board Member
General surgeon, practicing endovascular physician
A blend of interventional and engineering knowledge

Ram Reddy

AngioSafe co-founder, Investor, and Board Member
AngioSafe Board Chairman (2015-2025)
Seasoned Silicon Valley investor, entrepreneur, global company builder

Sanjay Tripathi

Founder and Managing Partner, Ananta Ventures
Angiosafe Board Member
Board Member, Pharmanova and Atlantic Lifesciences

Clinical Advisors

Driven by patients, guided by physicians, we are transforming the future of vascular intervention.

Subhash Banerjee, M.D., FACC, FSCAI

National Principal Investigator, AngioSafe Peripheral program
Chief of Cardiovascular Research and Innovation for Baylor Scott & White Heart and Vascular Hospital